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(2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol

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Origin: China

Cas No: 42200-33-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 42200-33-9 Formula: C17H27NO4 Molecular Weight: 309.40100

Description

β-Adrenergic blocker. Antihypertensive; antianginal.

Basic Info

Chemical Name	(2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
Synonyms	Nadololum [INN-Latin]; Corgaretic; nadolol; Solgol; (2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol; Anabet; Corgard; 5-[3-[(1,1-dimethylethyl)-amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-2,3-cis-naphthalenediol; 5-[3-(tert-butylamino)-2-oxopropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol; Nadic; [14C]-Nadolol; Nadololum; 1-tert.-butylamino-3-(1,2,3,4-tetrahydro-2,3-dihydroxy-5-napthyloxy)-2-propanol;
CAS No.	42200-33-9
Molecular Formula	C17H27NO4
Molecular Weight	309.40100
PSA	81.95000
LogP	1.02570

Properties

Appearance & Physical State	White Solid
Density	1.189g/cm3
Boiling Point	526.4ºC at 760mmHg
Melting Point	125-130ºC
Flash Point	272.2ºC
Refractive Index	1.573
Storage Condition	Refrigerator

Safety Info

HS Code	2922509090

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - man	571 ug/kg	1.Sense Organs and Special Senses (Eye)-visual field changes
Oral	TDLo - Lowest published toxic dose	Human - man	64 mg/kg/4W-I	1.Gastrointestinal-changes in structure or function of endocrine pancreas
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	5300 mg/kg	1.Details of toxic effects not reported other than lethal dose value

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