Início > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

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Origem: China

Cas No: 119302-20-4

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Quick Details
CAS No.:
119302-20-4
Other Names:
119302-20-4
MF:
C27H46N2O3, C27H46N2O3
EINECS No.:
601-595-5
Place of Origin:
Shandong China, Shandong China
Type:
Pharmaceutical Intermediates
Purity:
99.0%min, 99%
Brand Name:
Fousi, Fousi
Model Number:
FS119302-20-4
Application:
/, Pharmaceutical use
Appearance:
White Powder, powder
Product name:
3 17-DIHYDROXY-2-(4-MORPHOLINYL)-16-(1-PYRROLINYL)-ANDROSTANE
Form:
Powder
CAS:
119302-20-4
EINECS:
601-595-5
Packaging&Delivery
Packaging Details
Aluminum Foil bag/ drum/ bottle on request
Or as per customers required
Port
QINGDAO ,SHANGHAI
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 7 To be negotiated

Property

CAS No.: 119302-20-4 Formula: C27H46N2O3 Molecular Weight: 446.66600

Description

This compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.

Basic Info

Chemical Name	(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
Synonyms	2,3-Epoxy-1H-cyclopenta[a]phenanthrene,anddrostan-17-ol deriv; 2,3-Epoxy-1H-cyclopenta[a]phenanthrene,anddrostan-17-ol; 3,17-DIHYDROXY-2-(4-MORPHOLINYL)-16-(1-PYRROLINYL)-ANDROSTANE; RocuroniuM BroMide InterMediate VII; (2Beta,3Alpha,5Alpha,16Beta,17Beta)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol; Androstane-3,17-diol,2-(4-morpholinyl)-16-(1-pyrrolidinyl); 3,17-dihydroxy-2-(4-morpholinyl)-16-(1-pyrroliny)-androstane; 2-(4-MORPHOLINYL)-16-(1-PYRROLIDINYL)-5-ANDROSTANE-3,17-DIOL; (2b,3a,5a,16b,17b)-2-(4-Morphlinyl)-16-(1-Pyrrolidinyl)androstene-3,17-diol;
CAS No.	119302-20-4
Molecular Formula	C27H46N2O3
Molecular Weight	446.66600
PSA	56.17000
LogP	3.01170

Properties

Appearance & Physical State	Whitish or yellowish crystalline powder
Density	1.163
Boiling Point	565.4ºC at 760 mmHg
Melting Point	161-169ºC
Flash Point	295.7ºC
Refractive Index	1.574
Vapor Pressure	3.88E-15mmHg at 25°C

Synthesis Route

morpholine+(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol→(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
morpholine+(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol→(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol+(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol

Precursor

(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol
morpholine

Downstream Product

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
(2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)-3,17-bis(acetyloxyoxy)androstane
AND017

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