Home > Chiral Compounds> (2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

(2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

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Origin: China

Cas No: 20866-56-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 20866-56-2 Formula: C18H22N2O7 Molecular Weight: 378.37600

Basic Info

Chemical Name	(2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Synonyms	BOC-TYR-GLY-GLY-PHE-LEU-OH; Boc-Tyr-OSu; tert-butyloxycarbonyltyrosyl-glycyl-glycyl-phenylalanyl-leucine; N-tert-butyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine; Boc-Tyr-Gly-Gly-Phe-Leu; N-tertiarybutoxycarbonyl-L-tyrosine N-hydroxysuccinimide ester;
CAS No.	20866-56-2
Molecular Formula	C18H22N2O7
Molecular Weight	378.37600
PSA	122.24000
LogP	1.76400

Properties

Density	1.35g/cm3
Melting Point	-190ºC (dec.)
Refractive Index	1.581
Storage Condition	-20ºC

Synthesis Route

(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate+Sulfurous acid, bis(2,5-dioxo-1-pyrrolidinyl) ester→(2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate+(2,5-dioxopyrrolidin-1-yl) 1,2,2,2-tetrachloroethyl carbonate→(2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
N-Hydroxysuccinimide+(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate→(2,5-dioxopyrrolidin-1-yl) 3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Precursor

(2,5-dioxopyrrolidin-1-yl) 1,2,2,2-tetrachloroethyl carbonate
N-Hydroxysuccinimide
tert-butoxycarbonyl anhydride
Sulfurous acid, bis(2,5-dioxo-1-pyrrolidinyl) ester

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