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methyl (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

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Origin: China

Cas No: 837430-11-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 837430-11-2 Formula: C15H19F2NO4 Molecular Weight: 315.31200

Basic Info

Chemical Name	methyl (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Synonyms
CAS No.	837430-11-2
Molecular Formula	C15H19F2NO4
Molecular Weight	315.31200
PSA	64.63000
LogP	2.96450

Safety Info

HS Code	2924299090

Synthesis Route

2-tert-butoxycarbonylamino-3-(2,5-difluorophenyl)-acrylic acid methyl ester→methyl (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
tert-butoxycarbonyl anhydride+(2R,5S)-2,5-dihydro-3,6-dimethoxy-2-[(2',5'-difluorophenyl)methyl]-5-isopropylpyrazine→methyl (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
2,5-Difluorobenzyl bromide→methyl (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Precursor

tert-butoxycarbonyl anhydride
(2R,5S)-2,5-dihydro-3,6-dimethoxy-2-[(2',5'-difluorophenyl)methyl]-5-isopropylpyrazine
2-tert-butoxycarbonylamino-3-(2,5-difluorophenyl)-acrylic acid methyl ester
2,5-Difluorobenzyl bromide

Downstream Product

(2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

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