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methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

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Origin: China

Cas No: 4326-36-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
4326-36-7
MF:
C15H21NO5, C15H21NO5
EINECS No.:
1533716-785-6
Place of Origin:
Shandong China
Type:
Pharmaceutical Intermediates, Pharmaceutical Intermediates
Purity:
NLT98%, NLT98%
Brand Name:
Natural Micron Pharm Tech
Model Number:
4326-36-7
Application:
Pharmaceutical Intermediates
Appearance:
White to pale yellow Powder or Crystalline Powder
Product name:
Boc-L-Tyrosine methyl ester
CAS:
4326-36-7
EINECS:
1533716-785-6
MW:
295.33
Melting point:
100-104 °C(lit.)
Grade:
Medicine Grade
Test Method::
HPLC
Packaging&Delivery
Packaging Details
Packing Method: Aluminium Foil Bags/Drums
Port
Qingdao Port/Shanghai Port
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 5 To be negotiated

Property

CAS No.: 4326-36-7 Formula: C15H21NO5 Molecular Weight: 295.33100

Basic Info

Chemical Name	methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Synonyms	N-(tert-Butoxycarbonyl)-L-tyrosine methyl ester,Boc-L-tyrosine methyl ester; N-Boc-L-tyrosine Methyl Ester; N-t-butyloxycarbonyl-S-tyrosine methyl ester; N-(tert-Butoxycarbonyl)-L-tyrosine Methyl Ester; Boc-Tyr-Ome; Boc-L-Tyrosinemethylester; Boc-L-Tyrosine Methyl Ester;
CAS No.	4326-36-7
Molecular Formula	C15H21NO5
Molecular Weight	295.33100
PSA	84.86000
LogP	2.39190

Properties

Density	1.169 g/cm3
Boiling Point	452.7ºC at 760 mmHg
Melting Point	100-104ºC
Flash Point	227.6ºC
Refractive Index	50 ° (C=1, MeOH)
Storage Condition	-15ºC

Safety Info

WGK Germany	3

Synthesis Route

tert-butoxycarbonyl anhydride+methyl L-tyrosinate→methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
tert-butoxycarbonyl anhydride+Methyl L-tyrosinate hydrochloride→methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Methanol+tert-butoxycarbonyl anhydride→methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Precursor

tert-butoxycarbonyl anhydride
methyl L-tyrosinate
Methyl L-tyrosinate hydrochloride
(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Downstream Product

(S)-4-(2-Amino-3-hydroxypropyl)phenol
L-thyroxine
L-Tyrosine
Methyl L-tyrosinate hydrochloride

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