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methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

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Origin: China

Cas No: 112196-57-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 112196-57-3 Formula: C21H35NO5Si Molecular Weight: 409.59200

Basic Info

Chemical Name	methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-O-[(1,1-dimethylethyl)dimethylsilyl]-L-tyrosine Methyl Ester; O-tert-Butyldimethylsilyl-N-t-butoxycarbonyl-L-tyrosine,Methyl Ester;
CAS No.	112196-57-3
Molecular Formula	C21H35NO5Si
Molecular Weight	409.59200
PSA	77.35000
LogP	4.88380

Properties

Density	1.033g/cm3
Boiling Point	468.468ºC at 760 mmHg
Flash Point	237.121ºC
Refractive Index	1.486
Vapor Pressure	0mmHg at 25°C

Synthesis Route

methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate+tert-butyldimethylsilyl chloride→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
methyl L-tyrosinate→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
L-Tyrosine→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate

Precursor

tert-butyldimethylsilyl chloride
methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
methyl L-tyrosinate
L-Tyrosine

Downstream Product

methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate
(2S)-3-(4-hydroxyphenyl)-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoic acid

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