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2'-deoxyadenosine

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Origin: China

Cas No: 958-09-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    958-09-8
    Other Names:
    2'-Deoxyadenosine
    MF:
    C10H13N5O3
    EINECS No.:
    213-488-7
    Place of Origin:
    Shandong, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    98.0%min
    Brand Name:
    ENCH
    Model Number:
    ench-958-09-8
    Application:
    Pharm Intermediates
    Appearance:
    White Crystalline Solid, White Crystalline Solid
    Melting point:
    187-189 °C
    Color:
    White
    Molecular Weight:
    251.24
    Density:
    1.2938 (rough estimate)
    Brand:
    ENCH
    Packing:
    1kg/bag
    Boiling point:
    394.4°C (rough estimate)
    Form:
    Solid
    Shelf life:
    2 years

    Packaging&Delivery

    Packaging Details
    25G,1KG,25KG/drum or your demand.
    Port
    China main ports

  • Property

    CAS No.: 958-09-8 Formula: C10H13N5O3 Molecular Weight: 251.24200

    Description

    Deoxyadenosine (symbol dA or dAdo) is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA.
    In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).

    Basic Info

    Chemical Name 2'-deoxyadenosine
    Synonyms

    DESOXYADENOSINE;
    adeninedeoxyribose;
    Adenosine,2'-deoxy;
    DEOXYADENOSINE;
    2'-Deoxyadenosine;
    DEOXYADENOSINE-2';
    Adenyldeoxyriboside;
    Adenosine, 2‘-deoxy-;

    CAS No. 958-09-8
    Molecular Formula C10H13N5O3
    Molecular Weight 251.24200
    PSA 119.31000
    LogP -0.36960

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.91g/cm3
    Boiling Point 627.2ºC at 760 mmHg
    Melting Point 187-189ºC
    Flash Point 333.1ºC
    Refractive Index 1.863
    Storage Condition 2-8ºC

    Safety Info

    HS Code 2934999090
    WGK Germany 3

    Synthesis Route

    5'-d(TATT)-3'→thymidine+2'-deoxyadenosine
    →2'-deoxyguanosine+putrescinylthymidine
    →2'-deoxyguanosine+putrescinylthymidine

    Precursor

    2'-deoxyuridine
    2'-deoxy-3',5'-O-TIPDS-adenosine
    2'-iodo-2'-deoxyadenosine
    2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)adenosine

    Downstream Product

    2',3'-Dideoxyadenosine
    N-Benzoyl-2'-deoxy-adenosine
    2-deoxy-D-ribose
    3'-5'-DI-O-ACETYL-2'-DEOXYINOSINE

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