Home > Heterocyclic Compounds> N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

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Origin: China

Cas No: 64325-78-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 64325-78-6 Formula: C38H35N5O6 Molecular Weight: 657.71400

Basic Info

Chemical Name	N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
Synonyms	N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide;
CAS No.	64325-78-6
Molecular Formula	C38H35N5O6
Molecular Weight	657.71400
PSA	129.85000
LogP	5.82590

Properties

Appearance & Physical State	WHITE TO WHITE WITH A YELLOW CAST POWDER
Density	1.32 g/cm3
Melting Point	94ºC
Refractive Index	-10 ° (C=1, MeOH)
Storage Condition	-20ºC

Safety Info

Safety Statements	S22-S24/25
WGK Germany	3
Risk Statements	R20/21/22; R36/37/38
Hazard Codes	Xn

Synthesis Route

4,4'-Dimethoxytrityl chloride+N-Benzoyl-2'-deoxy-adenosine→N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
Triethylammonium 6-N-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 3'-H-phosphonate→N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
2'-deoxyadenosine→N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

Precursor

Triethylammonium 6-N-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 3'-H-phosphonate
N-Benzoyl-2'-deoxy-adenosine
O-2-cyanoethyl 5'-O-dimethoxytrityl-N6-benzoyldeoxyadenosin-3'-yl phosphonate
2'-deoxyadenosine

Downstream Product

5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-ol
DMT-dA(bz) Phosphoramidite
N-Benzoyl-2'-deoxy-adenosine
2'-deoxyadenosine

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