Home > Carbonyl Compounds> 2-Chloro-2,2-Difluoroacetophenone

2-Chloro-2,2-Difluoroacetophenone

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Origin: China

Cas No: 384-67-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 384-67-8 Formula: C8H5ClF2O Molecular Weight: 190.57500

Basic Info

Chemical Name	2-Chloro-2,2-Difluoroacetophenone
Synonyms	2-Chloro-2,2-difluoro-1-phenylethanone; 2-CHLORO-2,2-DIFLUOROACETOPHENONE;
CAS No.	384-67-8
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57500
PSA	17.07000
LogP	2.70090

Properties

Density	1.293 g/mL at 25 °C(lit.)
Boiling Point	94ºC(35 torr)
Flash Point	163 °F
Refractive Index	n20/D 1.497(lit.)

Safety Info

Safety Statements	S26-S36/37/39
HS Code	2914700090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H315; H319; H335
Signal Word	Warning
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

2,2-difluoro-2-fluorosulfonylacetyl fluoride+Benzene→2,2-DIFLUOROACETOPHENONE+2-Chloro-2,2-Difluoroacetophenone
(2,2-difluoro-1-phenylethenoxy)-trimethylsilane→2-Chloro-2,2-Difluoroacetophenone
Benzene→2-Chloro-2,2-Difluoroacetophenone

Precursor

Benzene
2-chloro-2,3-difluoro-3-phenyloxirane
phenylmagnesium bromide
(2,2-difluoro-1-phenylethenoxy)-trimethylsilane

Downstream Product

α-(Chlorodifluoromethyl)styrene
1,2,2-trifluoroethenylbenzene
2,2-DIFLUOROACETOPHENONE
3-(TRIFLUOROMETHYL)STYRENE

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