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2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine

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Origin: China

Cas No: 86-80-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 86-80-6 Formula: C17H24N2O Molecular Weight: 272.38500

Description

Quinisocaine (INN) or dimethisoquin (BAN and USAN) is a topical anesthetic used as an antipruritic.

Basic Info

Chemical Name	2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine
Synonyms	Histaderme; Pruralgin; Prulantex; dimethisoquin; Ethanamine, 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethyl-; Isochinol; Pruralgan; 2-[(3-butyl-1-isoquinolinyl)oxy]-N,N-dimethyl-ethanamine; Quinoleine; Chinisocain; Quinisocaine; Quinisocain; [2-(3-butyl-isoquinolin-1-yloxy)-ethyl]-dimethyl-amine; 3-Butyl-1-(2-dimethylamino-aethoxy)-isochinolin; 3-butyl-1-(2-dimethylamino-ethoxy)-isoquinoline;
CAS No.	86-80-6
Molecular Formula	C17H24N2O
Molecular Weight	272.38500
PSA	25.36000
LogP	3.51780

Properties

Density	1.034g/cm3
Boiling Point	388.3ºC at 760 mmHg
Flash Point	188.6ºC
Refractive Index	1.561

Synthesis Route

N,N-dimethylethanolamine sodium salt+3-butyl-1-chloro-isoquinoline→2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine
3-butyl-2H-isoquinolin-1-one→2-(3-butylisoquinolin-1-yl)oxy-N,N-dimethylethanamine

Precursor

3-butyl-2H-isoquinolin-1-one
3-butyl-1-chloro-isoquinoline
N,N-dimethylethanolamine sodium salt

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