Home > Chiral Compounds> (1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one

(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one

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Origin: China

Cas No: 53-39-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 53-39-4 Formula: C19H30O3 Molecular Weight: 306.44000

Description

A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.

Basic Info

Chemical Name	(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one
Synonyms	Oxandrin; Vasorome; oxandrolone; Lonavar; Protivar; Oxandrolonum; Provitar; Oxandrolona; Ossandrolone;
CAS No.	53-39-4
Molecular Formula	C19H30O3
Molecular Weight	306.44000
PSA	46.53000
LogP	3.54310

Properties

Appearance & Physical State	White crystalline powder
Density	1.105g/cm3
Boiling Point	444.4ºC at 760mmHg
Melting Point	235-238ºC
Flash Point	179.1ºC
Refractive Index	1.526
Storage Condition	Controlled Substance, -20ºC Freezer

Safety Info

RTECS	RN6800700
HS Code	2937290022
Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Declaration	H312 + H332; H360
Caution Statement	P201; P280; P308 + P313

Synthesis Route

(4aS,4bS,6aS,7S,9aS,9bR,11aS)-7-(methoxymethoxy)-4a,6a,7-trimethyltetradeca-hydroindeno[4,5-h]isochromen-2(1H)-one→(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one
(1S,3aS,3bS,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-3,3a,3b,4,5,5a,6,9b,10,11-decahydro-2H-indeno[4,5-h]isochromene-7,9-dione→(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one
17α-Methyl-1,2-Seco-A-nor-5α-androstan-1,2,17β-triol→(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	>10 gm/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	4893 mg/kg	1.Behavioral-somnolence (general depressed activity) 2.Behavioral-tremor 3.Behavioral-convulsions or effect on seizure threshold
Subcutaneous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	>10 gm/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

(4aS,4bS,6aS,7S,9aS,9bR,11aS)-7-(methoxymethoxy)-4a,6a,7-trimethyltetradeca-hydroindeno[4,5-h]isochromen-2(1H)-one
17β-hydroxy-17α-methyl-1,3-seco-2-nor-5α-androstane-1,3-diacid 1,3-dimethylester
(3S,3aS,5aS,6S,7S,9aS,9bS)-7-(carboxymethyl)-3-hydroxy-3,3a,6-trimethyldodecahydro-1H-cyclopenta[a]naphthalene-6-carboxylic acid
(1S,3aS,3bS,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-3,3a,3b,4,5,5a,6,9b,10,11-decahydro-2H-indeno[4,5-h]isochromene-7,9-dione

Downstream Product

(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one

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