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(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid

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Origin: China

CasNo: 220352-36-3

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Description

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CAS No.: 220352-36-3 Formula: C10H8F2O2 Molecular Weight: 198.16600

Basic Info

Chemical Name	(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
Synonyms	trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid; trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid; (1R,2R)-trans-2-(3,4-difluorophenyl)-1-cyclopropanecarboxylic acid; (1R-trans)-2-(3,4-difluorophenyl)-cyclopropanecarboxylic acid; (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid; (1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxylic acid;
CAS No.	220352-36-3
Molecular Formula	C10H8F2O2
Molecular Weight	198.16600
PSA	37.30000
LogP	2.15290

Synthesis Route

ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate→(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
3,4-Difluorobenzaldehyde→(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
4-ethenyl-1,2-difluorobenzene→(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid

Precursor

3,4-Difluorobenzaldehyde
ethyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
trans-3,4-Difluorocinnamic acid
4-ethenyl-1,2-difluorobenzene

Downstream Product

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride (1:1 )
ticagrelor
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide

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