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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Respiratory system> 1-cyclopentyl-N-methylpropan-2-amine
Picture of 1-cyclopentyl-N-methylpropan-2-amine

1-cyclopentyl-N-methylpropan-2-amine

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Origin: China

Cas No: 102-45-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 102-45-4 Formula: C9H19N Molecular Weight: 141.25400

    Description

    Cyclopentamine (trade names Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos, among others) is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely discontinued possibly due to the availability, effectiveness, and safety of a structurally similar drug, propylhexedrine.

    Basic Info

    Chemical Name 1-cyclopentyl-N-methylpropan-2-amine
    Synonyms

    Cyclonarol;
    cyclopentaimine;
    Sinos;
    Cyclopentadrin;
    Cyklosan;
    Cyclopentamine;
    Cyclopentamin;
    Cyclopentaneethanamine, N,α-dimethyl-;

    CAS No. 102-45-4
    Molecular Formula C9H19N
    Molecular Weight 141.25400
    PSA 12.03000
    LogP 2.56550

    Properties

    Density 0.838g/cm3
    Boiling Point 171.8ºC at 760mmHg
    Flash Point 45.5ºC
    Refractive Index 1.449
    Vapor Pressure 1.37mmHg at 25°C

    Safety Info

    HS Code 2921300090

    Synthesis Route

    1-cyclopentylpropan-2-one+METHYLAMINE→1-cyclopentyl-N-methylpropan-2-amine
    2-cyclopentylacetonitrile→1-cyclopentyl-N-methylpropan-2-amine
    2-(cyclopenten-1-yl)acetonitrile→1-cyclopentyl-N-methylpropan-2-amine

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed SE-30 140. 1100. isothermal
    Packed Apiezon L 100. 1076. isothermal
    Capillary DB-1 - 1085. temperature ramp
    Capillary DB-1 - 1085. temperature ramp
    Capillary SE-30 - 1065. temperature ramp

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous LDLo - Lowest published lethal dose Rodent - mouse 100 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    1-cyclopentylpropan-2-one
    2-cyclopentylacetonitrile
    2-(cyclopenten-1-yl)acetonitrile
    1-cyclopentylpropan-2-amine

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