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1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane

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Origin: China

Cas No: 848-53-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 848-53-3 Formula: C19H23ClN2 Molecular Weight: 314.85200

Description

Homochlorcyclizine (INN) is an antihistamine which has been marketed in Japan since 1965. It is used in the treatment of allergies and other conditions. It also has some anticholinergic, antidopaminergic, and antiserotonergic properties.

Basic Info

Chemical Name	1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane
Synonyms	Curosajin; Homoclomine; Homorestar; 1-(4-Chlor-benzhydryl)-4-methyl-hexahydro-[1,4]diazepin; Homochlorocyclizine; Homodamon; Lysilan; Homochlorcyclizine; Cromon S (base); Sankumin; Wicron; 1-(4-chloro-benzhydryl)-4-methyl-hexahydro-[1,4]diazepine; 1H-1,4-Diazepine, 1-[(4-chlorophenyl)phenylmethyl]hexahydro-4-methyl-; 1-(4-chloro-benzhydryl)-4-methyl-[1,4]diazepane;
CAS No.	848-53-3
Molecular Formula	C19H23ClN2
Molecular Weight	314.85200
PSA	6.48000
LogP	3.94270

Properties

Density	1.122 g/cm3
Boiling Point	403.9ºC at 760mmHg
Flash Point	198.1ºC
Refractive Index	1.58

Synthesis Route

1-Methyl-1,4-diazepan-5-one→1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane
N-Methylhomopiperazine+4-Chlorobenzhydrylchloride→1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane

Precursor

4-Chlorobenzhydrylchloride
1-Methyl-1,4-diazepan-5-one
N-Methylhomopiperazine

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