Início > Chiral Compounds> (-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one

(-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one

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Origem: China

Cas No: 90365-57-4

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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CAS No.: 90365-57-4 Formula: C17H23N3O2 Molecular Weight: 301.38300

Basic Info

Chemical Name	(-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
Synonyms	indolactam V;
CAS No.	90365-57-4
Molecular Formula	C17H23N3O2
Molecular Weight	301.38300
PSA	68.36000
LogP	2.05570

Properties

Appearance & Physical State	White to off-white solid.
Density	1.166 g/cm3
Boiling Point	584ºC at 760 mmHg
Melting Point	205.4 - 207.4 °C
Flash Point	307ºC
Refractive Index	1.589
Storage Condition	-20ºC

Synthesis Route

(S)-2-[3-((S)-2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-1H-indol-4-ylamino]-3-methyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester→(-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
DL-4-nitrotryptophan ethyl ester→(-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
1-(t-butoxycarbonyl)-3-hydroxymethyl-4-(N-methylamino)indole→(-)-Indolactam V,(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one

Precursor

(S)-2-[3-((S)-2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-1H-indol-4-ylamino]-3-methyl-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester
1-(t-butoxycarbonyl)-3-hydroxymethyl-4-(N-methylamino)indole
DL-4-nitrotryptophan ethyl ester
(S)-3-Methyl-2-(toluene-4-sulfonylamino)-butyric acid (S)-2-tert-butoxycarbonylamino-3-(4-nitro-1H-indol-3-yl)-propyl ester

Downstream Product

(-)-7-bromo-14-O-TBDMS-indolactam-V
(-)-7-n-octyl-14-O-TBDMS-indolactam-V
(-)-7-(trans-1-octenyl)-14-O-TBDMS-indolactam-V

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