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Tolcapone

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Origin: China

Cas No: 134308-13-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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CAS No.: 134308-13-7 Formula: C14H11NO5 Molecular Weight: 273.24100

Description

Tolcapone (brand name Tasmar) is a drug used to treat Parkinson's disease (PD). It is a selective, potent and reversible nitro catechol type inhibitor of enzyme catechol-O-methyl transferase (COMT).
Rat Catechol-O-methyltransferase bound to Tolcapone. PDB entry 3s68

Basic Info

Chemical Name	Tolcapone
Synonyms	UNII-CIF6334OLY; 1-(3,4-dihydroxy-5-nitrophenyl)-1-(4-methylphenyl)methanone; Tasmar (TN); 3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone; Methanone,(3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl); 4'-methyl-3,4-dihydroxy-5-nitro-benzophenone; Tasmar; (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone; Ro 40-7592; (3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone; [14C]-Tolcapone;
CAS No.	134308-13-7
Molecular Formula	C14H11NO5
Molecular Weight	273.24100
PSA	103.35000
LogP	3.06860