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Tiopronin

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Origem: China

Cas No: 1953-02-2

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

Quick Details
CAS No.:
1953-02-2
Other Names:
Tiopronin
MF:
C5H9NO3S
EINECS No.:
217-778-4
Place of Origin:
Shanghai, China
Type:
Antipyretic Analgesics and NSAIDs
Grade Standard:
Medicine Grade
Brand Name:
SHXLCHEM
Model Number:
SHXL
Purity:
99%min
Product name:
Tiopronin
Melting point:
93-98 °C
Color:
White Solid
Molecular Weight:
163.19
Fp:
N/A
Packing:
25kg/drum
CAS:
1953-02-2
Packaging&Delivery
Packaging Details
25G,1KG,25KG/drum or your demand.
Port
China main ports

Property

CAS No.: 1953-02-2 Formula: C5H9NO3S Molecular Weight: 163.19500

Description

Tiopronin (trade name Thiola) is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria. Due to the rarity of the disorder, tiopronin falls under the classification of an orphan drug. It is somewhat similar to penicillamine in both chemistry and pharmacology.

Basic Info

Chemical Name	Tiopronin
Synonyms	N-(2-Mercaptopropionyl)glycine; Sutilan; Capen; SF-572; Thiosol; Thiora; Thiola; Tioglis; Epatiol; N-2-Mercaptopropionyl-glycine; Vincol; 2-MPG;
CAS No.	1953-02-2
Molecular Formula	C5H9NO3S
Molecular Weight	163.19500
PSA	105.20000
LogP	-0.10360

Properties

Melting Point	93-98 °C
Vapor Pressure	3.6E-08mmHg at 25°C

Safety Info

RTECS	MC0596500
Safety Statements	S36/37
HS Code	2942000000
WGK Germany	3
Risk Statements	R22
Hazard Codes	Xn
Hazard Declaration	H302
Signal Word	Warning
Symbol	GHS07

Synthesis Route

(2-BROMO-PROPIONYLAMINO)-ACETIC ACID→Tiopronin
α-Ethylxanthogenpropionylglycin→Tiopronin
2-(2-benzoylsulfanylpropanoylamino)acetic acid→Tiopronin

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - woman	3120 mg/kg/26W-I	1.Blood-changes in serum composition (e.g. TP, bilirubin, cholesterol)
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1300 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1400 mg/kg	1.Details of toxic effects not reported other than lethal dose value