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GUSPERIMUS

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Origin: China

Cas No: 104317-84-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 104317-84-2 Formula: C17H37N7O3 Molecular Weight: 387.52100

    Description

    Gusperimus is an immunosuppressive drug. It is a derivative of the antitumor antibiotic spergualin, and inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells.
    Gusperimus was developed by Bristol-Myers Squibb. Currently, it is manufactured and sponsored for use as an orphan drug and for clinical studies by the Japanese company Euro Nippon Kayaku. The patent claim (see quotation) is that Gusperimus may be useful for a variety of hyperreactive inflammatory diseases such as autoimmune diseases. The drug is available in vials containing 100mg each.
    There is little information about the pharmacokinetic properties of gusperimus.

    Basic Info

    Chemical Name GUSPERIMUS
    Synonyms

    Deoxyspergualin;
    NKT-01;
    BMS-181 173;

    CAS No. 104317-84-2
    Molecular Formula C17H37N7O3
    Molecular Weight 387.52100
    PSA 178.38000
    LogP 1.75330

    Properties

    Density 1.26g/cm3
    Refractive Index 1.574

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