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cysteamine

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Origin: China

Cas No: 60-23-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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Product Description

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CAS No.: 60-23-1 Formula: C2H7NS Molecular Weight: 77.14870

Description

Cysteamine is the chemical compound with the formula HSCH2CH2NH2. It is the simplest stable aminothiol and a degradation product of the amino acid cysteine. It is often used as the hydrochloride salt, HSCH2CH2NH3Cl. The comparatively high melting point of cysteamine (95-97 °C), indicates that it exists in a salt form.

Basic Info

Chemical Name	cysteamine
Synonyms	2-Mercaptoethylamine; 2-AMINOETHANETHIOL; Ethanethiol, 2-amino-;
CAS No.	60-23-1
Molecular Formula	C2H7NS
Molecular Weight	77.14870
PSA	64.82000
LogP	0.57520

Properties

Appearance & Physical State	white powder
Density	0.973 g/cm3
Melting Point	95ºC
Flash Point	34.6ºC
Stability	Stable, but may be air-sensitive. Incompatible with strong oxidizing agents.
Storage Condition	2-8ºC

Safety Info

RTECS	KJ0175000
Safety Statements	S26-S36
WGK Germany	3
RIDADR	UN 3335
Risk Statements	R22; R36/37/38
Hazard Codes	Xn
Symbol	GHS07
Hazard Declaration	H302; H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

cystamine+potassium cyanide→4,5-dihydro-1,3-thiazol-2-amine+cysteamine
Glutathione+N5-((R)-3-((2-aminoethyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)glutamine→glutathione disulfide+cysteamine
Cysteamine hydrochloride→cysteamine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	232 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Subcutaneous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	84 mg/kg	1.Peripheral Nerve and Sensation-spastic paralysis with or without sensory change 2.Behavioral-convulsions or effect on seizure threshold 3.Skin and Appendages-hair
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	625 mg/kg	1.Details of toxic effects not reported other than lethal dose value