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tibolone

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Origin: China

Cas No: 5630-53-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 5630-53-5 Formula: C21H28O2 Molecular Weight: 312.44600

Basic Info

Chemical Name	tibolone
Synonyms	Tibolone; LIVIAL; 7a-Methyl-5,10-norethindrone; LIVIELLA; Org OD 14; 7a-Methyl-D5,10-norethindrone;
CAS No.	5630-53-5
Molecular Formula	C21H28O2
Molecular Weight	312.44600
PSA	37.30000
LogP	3.88260

Properties

Appearance & Physical State	white to off-white crystalline powder
Density	1.13g/cm3
Boiling Point	447.4ºC at 760mmHg
Melting Point	163 - 169ºC
Flash Point	190.6ºC
Refractive Index	105 ° (C=0.54, CH2Cl2/Et2O)
Storage Condition	2-8ºC

Safety Info

RTECS	RC8964020
Safety Statements	22-24/25-61
RIDADR	UN 3077 9/PG 3
Risk Statements	R51/53
Hazard Codes	N

Synthesis Route

2-Dehydro-3-methoxy Tibolone→tibolone
Tibolone 3-Ethylene Ketal→7.α.-Methyl-17-ethinyl-19-nortestosterone+tibolone
Tibolone 3-Dimethyl Ketal→7.α.-Methyl-17-ethinyl-19-nortestosterone+tibolone

Precursor

3-Methoxy-7α-methyl-estra-2,5(10)-dien-17β-ol
Tibolone 3-Ethylene Ketal
2-Dehydro-3-methoxy Tibolone
Tibolone 3-Dimethyl Ketal

Downstream Product

3β-Hydroxy Tibolone
3α-Hydroxy Tibolone

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