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tetrahydrofuran-3-carboxyaldehyde

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Origin: China

Cas No: 79710-86-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 79710-86-4 Formula: C5H8O2 Molecular Weight: 100.11600

Description

2-(Tetrahydrofuran-3-yl)acetaldehyde is a reagent used in the preparation of several pharmaceutical agents. It is used in the prepoaration of ortho-amino benzamides and nicotinamides as MCHr1 (Melanin-concentrating hormone receptor 1) antagonists, used in the therapeutic treatment of obesity. Also used in the pereparation of Tsg101-directed HIV-1 budding antagonists for application towards late-stage HIV-1 infection.

Basic Info

Chemical Name	tetrahydrofuran-3-carboxyaldehyde
Synonyms	3-Furancarboxaldehyde,tetrahydro; 3-formyltetrahydrofuran; tetrahydro-3-furancarbaldehyde; oxolane-3-carbaldehyde; tetrahydrofuran-3-carboxaldehyde; Tetrahydrofuran-3-carboxaldehyde solution; tetrahydrofuran-3-carbaldehyde;
CAS No.	79710-86-4
Molecular Formula	C5H8O2
Molecular Weight	100.11600
PSA	26.30000
LogP	0.22180

Properties

Density	1.106 g/mL at 25ºC
Boiling Point	99ºC
Flash Point	>230 °F
Refractive Index	n20/D 1.416

Safety Info

HS Code	2932190090
Risk Statements	R5

Synthesis Route

(S)-(Tetrahydrofuran-3-yl)methanol→tetrahydrofuran-3-carboxyaldehyde
2,5-Dihydrofuran+carbon monoxide→tetrahydrofuran-3-carboxyaldehyde
2,5-Dihydrofuran+carbon monoxide→tetrahydrofuran-2-carboxaldehyde+tetrahydrofuran-3-carboxyaldehyde

Precursor

Methyl tetrahydrofuran-3-carboxylate
2,5-Dihydrofuran
2,3-dihydrofuran
(S)-(Tetrahydrofuran-3-yl)methanol

Downstream Product

Tetrahydro-3-furoic acid
Tetrahydrofuran
3-METHYLTETRAHYDROFURAN
(S)-(Tetrahydrofuran-3-yl)methanol

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