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tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate

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Origin: China

Cas No: 194934-95-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
194934-95-7
Other Names:
O-tert-Butyl-3-keto Fluvastatin
MF:
C28H32FNO4
EINECS No.:
N/A
Place of Origin:
China
Type:
Agrochemical Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99min%
Brand Name:
Milliflux
Model Number:
API
Application:
Pharmaceutical Raw Intermediates
Appearance:
N/A
Packing:
25kg/drum or 20kg/bag
Assay:
99.0 %min
Storage:
Room Temperature
Shelf life:
Proper Storage
Grade:
EP,USP,CP,JP
Brand:
Milliflux
Website:
www.milliflux.com
Origin:
China
Packaging&Delivery
Selling Units:
Single item
Single package size:
50X50X50 cm
Single gross weight:
0.001 kg
Package Type:
```
Customer's request
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Lead Time:
Quantity(Boxes) 1 - 1 >1
Est. Time(days) 15 To be negotiated

Property

CAS No.: 194934-95-7 Formula: C28H32FNO4 Molecular Weight: 465.55600

Description

O-tert-Butyl-3-keto Fluvastatin is a reactant in the synthesis of Fluvastatin Sodium Salt, a synthetic HMG-CoA reductase inhibitor. Antilipemic.

Basic Info

Chemical Name	tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate
Synonyms	Fluvastatin tert-butyl ester; FHH: FLUVASTATIN INTERMEDIATE;
CAS No.	194934-95-7
Molecular Formula	C28H32FNO4
Molecular Weight	465.55600
PSA	68.53000
LogP	6.09340

Properties

Density	1.13
Boiling Point	647.7ºC at 760 mmHg
Refractive Index	1.552
Vapor Pressure	1.16E-17mmHg at 25°C

Synthesis Route

tert-Butyl acetate+(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate→(S)-(-)-1,1,2-Triphenylethane-1,2-diol+tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate

Precursor

(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate
(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
tert-Butyl acetate

Downstream Product

sodium,(E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoate
(3R,5S)-Fluvastatin tert-Butyl Ester

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