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tert-butyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate

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Origin: China

Cas No: 16874-12-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 16874-12-7 Formula: C13H19NO3 Molecular Weight: 237.29500

Description

L-Tyrosine tert-butyl ester is a protected form of L-Tyrosine. L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.

Basic Info

Chemical Name	tert-butyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate
Synonyms	H-Tyr-OtBu; tert-Butyl L-tyrosinate; L-tyrosine-COOBu-t; L-Tyrosine tert-butyl ester; t-butyl ester of tyrosine;
CAS No.	16874-12-7
Molecular Formula	C13H19NO3
Molecular Weight	237.29500
PSA	72.55000
LogP	2.30400

Properties

Appearance & Physical State	White to off-white crystalline powder
Density	1.125 g/cm3
Boiling Point	358.1ºC at 760 mmHg
Melting Point	141-144ºC
Flash Point	170.4ºC
Refractive Index	25 ° (C=2, EtOH)
Storage Condition	2-8ºC
Vapor Pressure	1.26E-05mmHg at 25°C

Safety Info

Safety Statements	S22-S24/25
HS Code	2922509090
WGK Germany	3

Synthesis Route

(S)-2-amino-3-(4-benzyloxy-phenyl)-tert-butyl-propionic ester→tert-butyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate
Z-TYR-OTBU H2O→tert-butyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate
Z-TYR-OH→tert-butyl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate

Precursor

Z-TYR-OTBU H2O
(S)-2-amino-3-(4-benzyloxy-phenyl)-tert-butyl-propionic ester
tert-Butyl acetate
L-Tyrosine

Downstream Product

Z-TYR-OTBU H2O
LHRH (1-5)
L-Tyrosine

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