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(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate

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Origin: China

Cas No: 82911-79-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 82911-79-3 Formula: C25H23NO5 Molecular Weight: 417.45400

Basic Info

Chemical Name	(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate
Synonyms	methyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoate;
CAS No.	82911-79-3
Molecular Formula	C25H23NO5
Molecular Weight	417.45400
PSA	84.86000
LogP	4.40590

Synthesis Route

N-(9-Fluorenylmethoxycarbonyloxy)succinimide+Methyl L-tyrosinate hydrochloride→(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate
methyl (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-(tert-butyldiphenylsilyl)ethoxy)phenyl)propanoate→(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate
9H-fluoren-9-ylmethyl carbonochloridate+Methyl L-tyrosinate hydrochloride→(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate

Precursor

diazomethane
9H-fluoren-9-ylmethyl carbonochloridate
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Methyl L-tyrosinate hydrochloride

Downstream Product

FMOC-TYR(MALONYL-DI-OTBU)-OH
FMOC-L-PHE(4-CH2-SO3H)
methyl L-tyrosinate
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid

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