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tanespimycin

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Origin: China

Cas No: 75747-14-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    75747-14-7
    Other Names:
    BAY579352
    MF:
    C31H43N3O8
    EINECS No.:
    N/A
    Place of Origin:
    Zhejiang, China
    Type:
    Auxiliaries and Other Medicinal Chemicals, Raw Material and Other Chemicals
    Grade Standard:
    Medicine Grade
    Brand Name:
    Crene
    Model Number:
    CAS 75747-14-7
    Purity:
    98% min
    Exact Mass:
    585.305
    Molecular Weight:
    585.688
    PSA:
    166.28
    LogP:
    3.9576
    Target:
    c-Kit; PDGFR; VEGFR
    Pathway:
    Protein Tyrosine Kinase/RTK
    Solubility:
    DMSO: ≥ 46 mg/mL
    Appearance:
    Solid powder

    Packaging&Delivery

    Packaging Details
    Packaging according to customer requirements.
    Port
    shanghai
    Lead Time:
    Quantity(Milligrams)1 - 5000>5000
    Est. Time(days)3To be negotiated
  • Property

    CAS No.: 75747-14-7 Formula: C31H43N3O8 Molecular Weight: 585.68800

    Description

    Tanespimycin (17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specific young patients with certain types of leukemia or solid tumors, especially kidney tumors.
    It works by inhibiting Hsp90, which is expressed in those tumors.
    It belongs to the family of drugs called antitumor antibiotics.

    Basic Info

    Chemical Name tanespimycin
    Synonyms

    17-AAG,17AAG;
    17-AG;
    17-AGG;
    17-AAG (Tanespimycin);
    KOS 953;
    Telatinib;
    [3H]-17-AAG;
    17-allylamino-17-demethoxygeldanamycin;
    Tanespimycin;
    17-AAG;
    Gld-36;
    17-AAG (KOS953);

    CAS No. 75747-14-7
    Molecular Formula C31H43N3O8
    Molecular Weight 585.68800
    PSA 166.28000
    LogP 3.95760

    Properties

    Appearance & Physical State Dark purple solid
    Density 1.21
    Boiling Point 797.8ºC at 760 mmHg
    Melting Point 201-203ºC
    Flash Point 436.3ºC
    Refractive Index 1.566
    Storage Condition -20ºC

    Safety Info

    Safety Statements S22; S24/25; S36; S26
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    Allylamine+geldanamycintanespimycin

    Precursor

    Allylamine
    geldanamycin

    Downstream Product

    17-allylamino-17-demethoxygeldanamycin hydroquinone
    17-Amino Geldanamycin

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