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suprofen

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Origin: China

Cas No: 40828-46-4

Specification: 99%min

Min order Quantity: 1 /kg

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    40828-46-4
    Other Names:
    R25061
    MF:
    C14H12O3S
    EINECS No.:
    N/A
    Place of Origin:
    Zhejiang, China
    Type:
    Auxiliaries and Other Medicinal Chemicals, Raw Material and Other Chemicals
    Grade Standard:
    Medicine Grade
    Brand Name:
    Crene
    Model Number:
    cas 40828-46-4
    Purity:
    98% min
    Exact Mass:
    260.05
    Molecular Weight:
    260.308
    PSA:
    82.61
    LogP:
    3.16720
    Appearance:
    Solid powder
    Target:
    PGE synthase
    Pathway:
    Immunology/Inflammation
    Solubility:
    DMSO : ≥ 100 mg/mL (384.16 mM)

    Packaging&Delivery

    Packaging Details
    Packaging according to customer requirements.
    Port
    shanghai
    Lead Time:
    Quantity(Milligrams)1 - 5000>5000
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 40828-46-4 Formula: C14H12O3S Molecular Weight: 260.30800

    Description

    Suprofen is a non-steroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica that was marketed as 1% eye drops under the trade name Profenal.

    Basic Info

    Chemical Name suprofen
    Synonyms

    p-(2-thenoyl)hydratropic acid;
    Profenol;
    Suprol;
    Suprocil;
    Anemet;
    Dolasteron;
    Profenal;
    Suprofen;
    Srendam;
    TN 762;
    2-(4-thenoyl)phenylpropanoic acid;
    maldocil;
    Topalgic;

    CAS No. 40828-46-4
    Molecular Formula C14H12O3S
    Molecular Weight 260.30800
    PSA 82.61000
    LogP 3.16720

    Properties

    Density 1.29 g/cm3
    Boiling Point 442.6ºC at 760 mmHg
    Melting Point 278ºC
    Flash Point 221.5ºC
    Refractive Index 1.612
    Stability Stable at normal temperatures and pressures.
    Storage Condition -20ºC Freezer

    Safety Info

    Hazard Class 6.1(b)
    HS Code 2934999090
    Packing Group III
    RIDADR UN 3249
    Symbol GHS06
    Signal Word Danger
    Hazard Declaration H301

    Synthesis Route

    carbon monoxide+4-vinylphenyl 2-thienyl ketone→suprofen
    diethyl 2-methyl-2-[4-(thiophene-2-carbonyl)phenyl]propanedioate→suprofen
    2-[4-(thiophene-2-carbonyl)phenyl]propanenitrile→suprofen

    Precursor

    4-(thien-2-ylcarbonyl)phenylacetic acid
    diethyl 2-methyl-2-[4-(thiophene-2-carbonyl)phenyl]propanedioate
    4-vinylphenyl 2-thienyl ketone
    2-[4-(thiophene-2-carbonyl)phenyl]propanenitrile

    Downstream Product

    decarboxysuprofen
    sodium,2-[4-(thiophene-2-carbonyl)phenyl]propanoate

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