Home > Aromatic Compounds> (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

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Origin: China

Cas No: 40371-50-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 40371-50-4 Formula: C12H15NO5 Molecular Weight: 253.25100

Description

(S)-(+)-Z-4-Amino-2-hydroxybutyric Acid is used in the synthesis of aminoglycoside antibiotics.

Basic Info

Chemical Name	(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
Synonyms	CBZ-HABA; (S)-(+)-Z-4-Amino-2-hydroxybutyric acid; 2-Hydroxy-4-Carbobenzyloxyaminobutyric Acid; (S)-N-Cbz-4-Amino-2-hydroxybutyric acid;
CAS No.	40371-50-4
Molecular Formula	C12H15NO5
Molecular Weight	253.25100
PSA	95.86000
LogP	1.13930

Properties

Appearance & Physical State	White flake crystalline
Density	1.311 g/cm3
Boiling Point	521.2ºC at 760 mmHg
Melting Point	72-78ºC
Flash Point	269ºC
Refractive Index	1.563
Storage Condition	Store in a cool, dry place. Store in a tightly closed container.

Safety Info

Safety Statements	S26-S36
HS Code	2924299090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

(2S)-4-amino-2-hydroxybutyric acid+Benzyl chloroformate→(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
azane,butanoic acid,formaldehyde,toluene,dihydrate→(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
methyl 2-oxo-4-(phenylmethoxycarbonylamino)butanoate→(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid

Precursor

Benzyl chloroformate
azane,butanoic acid,formaldehyde,toluene,dihydrate
methyl 2-oxo-4-(phenylmethoxycarbonylamino)butanoate
(2S)-4-amino-2-hydroxybutyric acid

Downstream Product

(2S)-4-amino-2-hydroxybutyric acid

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