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γ-Hydroxybutyric acid monosodium salt

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Origin: China

Cas No: 502-85-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 502-85-2 Formula: C4H8NaO3+ Molecular Weight: 127.09400

Description

Sodium oxybate (USAN) (brand names Xyrem, Alcover, Anetamin, Gamanest, Gioron, Somsanit), contracted from sodium γ-hydroxybutyrate, is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of excessive daytime sleepiness (EDS) associated with narcolepsy, and by the FDA, Health Canada and in some areas of the United Kingdom National Health Service for the treatment of cataplexy associated with narcolepsy. Sodium oxybate is the sodium salt of γ-hydroxybutyric acid (GHB). Xyrem is manufactured by Jazz Pharmaceuticals in the US and Valeant Pharmaceuticals in Canada. Under the name Alcover, it is used in Italy for treatment of alcohol withdrawal and dependence.

Basic Info

Chemical Name	γ-Hydroxybutyric acid monosodium salt
Synonyms	GHB SODIUM SALT; 4-hydroxybutyric acid sodium salt; somsanit; gammaoh; 4-Hydroxybutyrate sodium; SODIUM 4-HYDROXYBUTYRATE; sodium 4-hydroxybutanoate; SODIUM OXYBATE;
CAS No.	502-85-2
Molecular Formula	C4H8NaO3+
Molecular Weight	127.09400
PSA	57.53000
LogP	-0.15650

Properties

Boiling Point	295.6ºC at 760mmHg
Melting Point	145-146ºC
Flash Point	146.8ºC
Storage Condition	Controlled Substance, -20ºC Freezer

Safety Info

Safety Statements	S24/25
HS Code	2918199090

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - man	71 mg/kg	1.Behavioral-hallucinations, distorted perceptions 2.Behavioral-coma 3.Gastrointestinal-nausea or vomiting
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	9690 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1650 mg/kg	1.Details of toxic effects not reported other than lethal dose value