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Ranirestat

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Origin: China

Cas No: 147254-64-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 147254-64-6 Formula: C17H11BrFN3O4 Molecular Weight: 420.18900

    Description

    Ranirestat (also known as AS-3201) is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy by Dainippon Sumitomo Pharma and PharmaKyorin. It has been granted orphan drug status. The drug is to be used orally.

    Basic Info

    Chemical Name Ranirestat
    Synonyms

    AS-3201;
    (R)-2-(4-bromo-2-fluorobenzyl)spiro[1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4,3'-pyrrolidine]-1,2',3,5'-tetrone;
    Ranirestat (JAN/INN);
    R-(-)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydro[1,2-a]pyrrolopyridine-4-spiro-3'-pyrrolidine-1,2',3'5'-tetraone;
    (3R)-2'-[(4-bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5-tetrone;
    SX-3202;
    (3R)-2'-(4-bromo-2-fluorobenzyl)spiro[pyrrolidin-3,4'(1'H)-pyrrolo[1,2-a]pyrazin]-1',2,3',5(2'H)-tetraone;
    (3R)-2'-(4-bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'(1'H)-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2H')-tetraone;
    SX 3030;

    CAS No. 147254-64-6
    Molecular Formula C17H11BrFN3O4
    Molecular Weight 420.18900
    PSA 91.97000
    LogP 1.52790

    Properties

    Density 1.83g/cm3
    Boiling Point 702.7ºC at 760mmHg
    Flash Point 378.8ºC
    Refractive Index 1.749
    Vapor Pressure 1.36E-19mmHg at 25°C

    Safety Info

    Caution Statement P280; P304 + P340 + P312; P305 + P351 + P338; P337 + P313
    Symbol GHS07
    Signal Word Warning
    Hazard Declaration H315; H319; H335

    Synthesis Route

    4-Bromo-2-fluorobenzylamine+Ranirestat

    Precursor

    4-Bromo-2-fluorobenzylamine

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