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(R)-2-Amino-3,3-diphenylpropanoic acid

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Origin: China

Cas No: 149597-91-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 149597-91-1 Formula: C15H15NO2 Molecular Weight: 241.28500

Description

The most common use of the word Diphenylalanine refers to two Phenylalanine molecules joined together by a Peptide bond.
Diphenylalanine is an unnatural amino acid. It is similar to the two amino acids alanine and phenylalanine. It has been used for the synthesis of pseudopeptide analogues which are capable of inhibiting certain enzymes.
A possible synthesis starts from 3,3-diphenyl-propionic acid which is stereoselective aminated to the diphenylalanine.

Basic Info

Chemical Name	(R)-2-Amino-3,3-diphenylpropanoic acid
Synonyms	3,3-Diphenyl-D-alanine; D-β-diphenylalanine; (R)-2-amino-3,3-diphenylpropanoic acid;
CAS No.	149597-91-1
Molecular Formula	C15H15NO2
Molecular Weight	241.28500
PSA	63.32000
LogP	2.93070

Properties

Density	1.198g/cm3
Boiling Point	389.2ºC at 760mmHg
Flash Point	189.2ºC
Refractive Index	1.611
Storage Condition	Store at 0ºC
Vapor Pressure	9.35E-07mmHg at 25°C

Safety Info

Hazard Codes	Xi

Synthesis Route

methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate→3,3-Diphenyl-L-alanine+(R)-2-Amino-3,3-diphenylpropanoic acid
DL-3,3-Diphenylalanine→3,3-Diphenyl-L-alanine+(R)-2-Amino-3,3-diphenylpropanoic acid
Chlorodiphenylmethane→(R)-2-Amino-3,3-diphenylpropanoic acid

Precursor

DL-3,3-Diphenylalanine
Chlorodiphenylmethane
methyl 2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoate

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