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Picture of (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid

(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid

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Origin: China

CasNo: 1007358-76-0

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
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  • Property

    CAS No.: 1007358-76-0 Formula: C22H22N2O4 Molecular Weight: 378.42100

    Basic Info

    Chemical Name (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
    Synonyms

    Ambrisentan,(R);
    UNII-Q1BX7HE63A;
    (R)-ambrisentan;
    (|AS)-|A-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-|A-methoxy-|A-phenylbenzenepropanoic Acid;
    Ambrisentan;

    CAS No. 1007358-76-0
    Molecular Formula C22H22N2O4
    Molecular Weight 378.42100
    PSA 81.54000
    LogP 3.51560

    Synthesis Route

    (S)-1-(3-methoxyphenyl)ethylammonium (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionate+4,6-Dimethyl-2-methylsulfonylpyrimidine(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
    2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid

    Precursor

    4,6-Dimethyl-2-methylsulfonylpyrimidine
    2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
    (S)-1-(3-methoxyphenyl)ethylammonium (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionate

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