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poly(I:C)

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Origin: China

Cas No: 24939-03-5

Specification: 99%min

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Supply Ability: 100 mt/month

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    CAS No.: 24939-03-5 Formula: C19H27N7O16P2 Molecular Weight: 671.40300

    Description

    Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.
    Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.

    Basic Info

    Chemical Name poly(I:C)
    Synonyms

    Polyinosinicacid-polycytidylicacid;
    Polyinosinic–polycytidylic acid;
    polyri:polyrc;
    polyi:c;
    Poly(I).Poly(C);
    polycpolyi;
    5'-Inosinic acid homopolymer-5'-cytidylic acid homopolymer complex (1_1);
    Polyinosinic;

    CAS No. 24939-03-5
    Molecular Formula C19H27N7O16P2
    Molecular Weight 671.40300
    PSA 377.00000
    LogP -4.01670

    Properties

    Boiling Point 851.4ºC at 760 mmHg
    Storage Condition -20ºC
    Vapor Pressure 7.7E-31mmHg at 25°C

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