Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> phenylephrine hydrochloride

phenylephrine hydrochloride

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 61-76-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
CAS No.:
61-76-7
Other Names:
Phenylephrine HCL
MF:
C9H14ClNO2
EINECS No.:
200-517-3
Place of Origin:
Jiangsu, China
Type:
Pharmaceutical Intermediates
Purity:
99%
Brand Name:
JUMING
Model Number:
CAS 61-76-7
Application:
Pharmaceutical intermediate
Appearance:
White Powder
Sample:
Available
Molecular Weight:
203.66600
Packing:
25kg/Bag
Storage:
Cool and dry place
Boiling point:
341.1 C at 760 mmHg
Melting point:
143-145 C(lit.)
Flash point:
163.4 C
Packaging&Delivery
Packaging Details
25kg/Bag
Pallet can be avialable for bulk order.
Port
SHANGHAI
Lead Time:
Quantity(Kilograms) 1 - 1000 >1000
Est. Time(days) 15 To be negotiated

Property

CAS No.: 61-76-7 Formula: C9H14ClNO2 Molecular Weight: 203.66600

Description

Phenylephrine is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo. Phenylephrine can also cause a decrease in heart rate through reflex bradycardia.

Basic Info

Chemical Name	phenylephrine hydrochloride
Synonyms	consdrin; (R)-(-)-Phenylephrine (hydrochloride); almefrin; synasal; Phenylephrine hydrochloride; efricel; phenylephrine HCl; lexatol; uri; metaoxedrin; fenox; emagrin; fenilfar; rhinall;
CAS No.	61-76-7
Molecular Formula	C9H14ClNO2
Molecular Weight	203.66600
PSA	52.49000
LogP	1.83790

Properties

Appearance & Physical State	white to almost white crystalline powder
Boiling Point	341.1ºC at 760 mmHg
Melting Point	140-145ºC
Flash Point	163.4ºC
Refractive Index	-45.5 ° (C=1, H2O)
Water Solubility	>=10 g/100 mL at 21 ºC
Storage Condition	Desiccate at RT

Safety Info

RTECS	DO7525000
Hazard Class	6.1(b)
Safety Statements	S26-S37/39
HS Code	2937229000
Packing Group	III
WGK Germany	3
RIDADR	UN 3249
Risk Statements	R22; R36/37/38
Hazard Codes	Xn

Synthesis Route

1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride→phenylephrine hydrochloride
phenylephrine→phenylephrine hydrochloride
1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride→phenylephrine hydrochloride+3-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1)

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Ocular	TDLo - Lowest published toxic dose	Human - man	120 mg/kg	1.Brain and Coverings-changes in circulation (hemorrhage, thrombosis, etc.) 2.Behavioral-muscle weakness
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	350 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	17 mg/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

phenylephrine
(S)-2-(benzyl(methyl)amino)-1-(3-(benzyloxy)phenyl)ethanol hydrochloride
(R)-3-(1-hydroxy-2-iodoethyl)phenol
1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride

Downstream Product

DL-Phenylephrine Hydrochloride
(R)-5-(3-Hydroxyphenyl)-3-methyl-2-oxazolidinone

Hot tags: phenylephrine hydrochloride, China, manufacturers, suppliers, factory, wholesale, low price, high quality