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N-Cbz-4-(hydroxymethyl)piperidine

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Origin: China

Cas No: 122860-33-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 122860-33-7 Formula: C14H19NO3 Molecular Weight: 249.30600

Basic Info

Chemical Name	N-Cbz-4-(hydroxymethyl)piperidine
Synonyms	1-Cbz-4-Hydroxymethylpiperidine; Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate; N-Cbz-4-hydroxymethylpiperidine;
CAS No.	122860-33-7
Molecular Formula	C14H19NO3
Molecular Weight	249.30600
PSA	49.77000
LogP	1.96540

Properties

Appearance & Physical State	Brown Liquid
Density	1.162 g/cm3
Boiling Point	396.4ºC at 760 mmHg
Flash Point	193.5ºC
Refractive Index	1.549
Vapor Pressure	5.4E-07mmHg at 25°C

Safety Info

Safety Statements	S26; S36/37/39; S37/39
HS Code	2933399090
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4-Piperidinemethanol+Benzyl chloroformate→N-Cbz-4-(hydroxymethyl)piperidine
Ethyl 1-Cbz-Piperidine-4-Carboxylate→N-Cbz-4-(hydroxymethyl)piperidine
4-Piperidinemethanol+phenyl carbonochloridate→N-Cbz-4-(hydroxymethyl)piperidine

Precursor

Benzyl chloroformate
phenyl carbonochloridate
4-Piperidineethanol
4-Piperidinemethanol

Downstream Product

1-Cbz-4-Piperidinecarboxaldehyde
benzyl 4-[(4-methylphenyl)sulfonyloxymethyl]piperidine-1-carboxylate
1-Cbz-4-(Methylsulfonyloxymethyl)Piperidine
benzyl 4-(iodomethyl)piperidine-1-carboxylate

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