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Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate

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Origin: China

Cas No: 39945-51-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 39945-51-2 Formula: C14H19NO3 Molecular Weight: 249.30600

Basic Info

Chemical Name	Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate
Synonyms	1-Benzyloxycarbonyl-3-piperidinemethanol; N-Cbz-(3-hydroxymethyl)piperidine; benzyl 3-(hydroxymethyl)piperidine-1-carboxylate;
CAS No.	39945-51-2
Molecular Formula	C14H19NO3
Molecular Weight	249.30600
PSA	49.77000
LogP	1.96540

Properties

Appearance & Physical State	pale yellow oil.
Density	1.162 g/cm3
Boiling Point	396.4ºC at 760 mmHg
Flash Point	193.5ºC
Refractive Index	1.549

Safety Info

Safety Statements	S26; S36/37/39
HS Code	2933399090
Risk Statements	R36/37/38

Synthesis Route

3-Piperidinemethanol+Benzyl chloroformate→Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate
1-O-benzyl 3-O-ethyl piperidine-1,3-dicarboxylate→Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate
1-O-benzyl 3-O-ethyl (3R)-piperidine-1,3-dicarboxylate+benzyl 2-formylpiperidine-1-carboxylate→Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate

Precursor

Benzyl chloroformate
benzyl 2-formylpiperidine-1-carboxylate
3-Piperidinemethanol
1-O-benzyl 3-O-ethyl piperidine-1,3-dicarboxylate

Downstream Product

3-(1H-imidazol-5-yl)piperidine
benzyl 3-formylpiperidine-1-carboxylate
benzyl 3-(iodomethyl)piperidine-1-carboxylate

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