Home > Aromatic Compounds> N-Boc-L-Phenylalaninol

N-Boc-L-Phenylalaninol

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Origin: China

Cas No: 66605-57-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
66605-57-0
MF:
C14H21NO3, C14H21NO3
EINECS No.:
1533716-785-6
Place of Origin:
Shandong China
Type:
Pharmaceutical Intermediates, Pharmaceutical Intermediates
Purity:
NLT98%, NLT98%
Brand Name:
Natural Micron Pharm Tech
Model Number:
66605-57-0
Application:
Pharmaceutical Intermediates
Appearance:
White Powder
Product name:
N-Boc-L-Phenylalaninol
CAS:
66605-57-0
EINECS:
1533716-785-6
MW:
251.32
Melting point:
94-96 °C(lit.)
Grade:
Medicine Grade
Test Method::
HPLC
Packaging&Delivery
Packaging Details
Packing Method: Aluminium Foil Bags/Drums
Port
Qingdao Port/Shanghai Port
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 5 To be negotiated

Property

CAS No.: 66605-57-0 Formula: C14H21NO3 Molecular Weight: 251.32100

Description

Protected L-Phenylalaninol, an intermediate in the preparation of (R)-Amphetamine.

Basic Info

Chemical Name	N-Boc-L-Phenylalaninol
Synonyms	tert-butyl N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]carbamate;
CAS No.	66605-57-0
Molecular Formula	C14H21NO3
Molecular Weight	251.32100
PSA	58.56000
LogP	2.50560

Properties

Appearance & Physical State	white to light yellow crystal powder
Density	1.085 g/cm3
Boiling Point	410.1ºC at 760 mmHg
Melting Point	94-96ºC
Flash Point	201.8ºC
Storage Condition	-15ºC

Safety Info

Safety Statements	S24/25
HS Code	2924299090
WGK Germany	3
Risk Statements	R36/37/38

Synthesis Route

(1-carbamoyl-2-phenyl-ethyl)-carbamic acid tert-butyl ester→tert-Butyl carbamate+3-phenylpropanamide
Boc-L-Tyr-NH2→tert-Butyl carbamate+3-phenylpropanamide
tert-butoxycarbonyl anhydride+(2S)-2-amino-3-phenylpropan-1-ol→N-Boc-L-Phenylalaninol

Precursor

tert-butoxycarbonyl anhydride
N-Boc-L-phenylalanine ethyl ester
(S)-4,6-dimethoxy-1,3,5-triazin-2-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate
(2S)-2-amino-3-phenylpropan-1-ol

Downstream Product

(2S)-N<sup>1</sup>,N<sup>1</sup>-Dimethyl-3-phenyl-1,2-propanediamine
N-Boc-L-phenylalaninal
(S)-TERT-BUTYL 1-(TERT-BUTYLDIMETHYLSILYLOXY)-3-PHENYLPROPAN-2-YLCARBAMATE
(2S)-2-amino-3-phenylpropan-1-ol

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