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Cbz-D-Phenylalaninol

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Origin: China

Cas No: 58917-85-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 58917-85-4 Formula: C17H19NO3 Molecular Weight: 285.33800

Basic Info

Chemical Name	Cbz-D-Phenylalaninol
Synonyms	benzyl N-[(2R)-1-hydroxy-3-phenylpropan-2-yl]carbamate;
CAS No.	58917-85-4
Molecular Formula	C17H19NO3
Molecular Weight	285.33800
PSA	58.56000
LogP	2.90730

Properties

Appearance & Physical State	White to off-white microcrystalline powder
Density	1.175 g/cm3
Boiling Point	489ºC at 760 mmHg
Melting Point	92-95ºC
Flash Point	249.6ºC
Refractive Index	42 ° (C=2, MeOH)
Storage Condition	Store at 0-5ºC

Safety Info

Safety Statements	S22-S24/25
HS Code	2924299090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

D(+)-Phenylalaninol+Benzyl chloroformate→Cbz-D-Phenylalaninol
(2R)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoic acid→Cbz-D-Phenylalaninol
D(+)-Phenylalaninol+phenyl carbonochloridate→Cbz-D-Phenylalaninol

Precursor

Benzyl chloroformate
(2R)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoic acid
phenyl carbonochloridate
N-(Benzyloxycarbonyloxy)succinimide

Downstream Product

Ubenimex
benzyl N-[(2R)-1-oxo-3-phenylpropan-2-yl]carbamate
(4R,5S,6S,7R)-1,3,4,7-tetrabenzyl-5,6-dihydroxy-1,3-diazepan-2-one
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(naphthalen-2-ylmethyl)-1,3-diazepan-2-one

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