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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide
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N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide

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Origin: China

Cas No: 59729-31-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 59729-31-6 Formula: C22H27ClN2O Molecular Weight: 370.91600

    Description

    Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac and Wolff-Parkinson-White syndrome. Lorcainide was developed by Janssen Pharmaceutica (Belgium) in 1968 under the commercial name Remivox and is designated by code numbers R-15889 or Ro 13-1042/001. It has a half-life of 8.9 +- 2.3 hrs which may be prolonged to 66 hrs in people with cardiac disease .

    Basic Info

    Chemical Name N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide
    Synonyms

    N-(4-chloro-phenyl)-N-(1-isopropyl-piperidin-4-yl)-2-phenyl-acetamide;
    lorcainid;
    N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]benzeneacetamide;
    Lorcainidum [INN-Latin];
    LORCAINIDE;
    Lorcainida [INN-Spanish];
    Lorcainide [INN:BAN];
    Benzeneacetamide,N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl];
    4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide;

    CAS No. 59729-31-6
    Molecular Formula C22H27ClN2O
    Molecular Weight 370.91600
    PSA 23.55000
    LogP 4.72640

    Properties

    Density 1.161g/cm3
    Boiling Point 503ºC at 760 mmHg
    Flash Point 258ºC
    Refractive Index 1.594

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed OV-101 - 2815. temperature ramp

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