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N,O-Bis(trimethylsilyl)acetamide

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Origin: China

Cas No: 10416-59-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
10416-59-8
Other Names:
N,O-Bis(trimethylsilyl)acetamide
MF:
C8H21NOSi2, C8H21NOSi2
EINECS No.:
233-892-7
Place of Origin:
Shandong, China
Type:
Syntheses Material Intermediates
Purity:
99%min
Brand Name:
Look chemical
Model Number:
C-CAS 10416-59-8
Application:
Intermediate
Appearance:
Colorless liquid, Colorless liquid
NAME:
N,O-Bis(trimethylsilyl)acetamide
CAS:
10416-59-8
MW:
203.43
Storage:
Normal termperature
Stock:
Enough
Sample:
Available
Packing:
1kg/bottle,25kg/drum or as your requirement
Assay:
99%min
Packaging&Delivery
Packaging Details
1kg/bag,25kg/drum or as your requirement
Port
Any port you need

Property

CAS No.: 10416-59-8 Formula: C8H21NOSi2 Molecular Weight: 203.42900

Description

Bis(trimethylsilyl)acetamide (BSA) is an organosilicon compound with the formula Me3SiNC(OSiMe3)Me (Me = CH3). It is a colorless liquid that is soluble in diverse organic solvents, but reacts rapidly with compounds, including solvents and moisture, containing OH and NH functional groups. It is used in analytical chemistry for the derivatisation of compounds in analysis to increase their volatility, e.g. for gas chromatography. It is also used to introduce the trimethylsilyl protecting group in organic synthesis. A related reagent is N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA).

Basic Info

Chemical Name	N,O-Bis(trimethylsilyl)acetamide
Synonyms	TMS-BABSA; bsa kit; tms-ba kit; TMS-BA; Trimethylsilyl N-(trime; TMS-BA KitBSA Kit; CB2500; bis-TMS-acetamide; BSA; dynasylan bsa; (E)-Trimethylsilyl N-(trimethylsilyl)acetimidate; Trimethylsilyl N-(trimethylsilyl)acetimidate;
CAS No.	10416-59-8
Molecular Formula	C8H21NOSi2
Molecular Weight	203.42900
PSA	21.59000
LogP	3.09120

Properties

Appearance & Physical State	Clear to yellowish clear liquid
Density	0.823
Boiling Point	71-73ºC (35 torr)
Melting Point	24ºC
Flash Point	42ºC
Refractive Index	1.4165-1.4185
Stability	Stable under normal temperatures and pressures.
Storage Condition	0-6ºC

Safety Info

RTECS	AK3000000
Hazard Class	8
Safety Statements	S26-S30-S36-S43-S7/8
HS Code	29310095
Packing Group	II
WGK Germany	3
RIDADR	UN 2920
Risk Statements	R10; R14; R22; R34
Hazard Codes	C

Synthesis Route

N-trimethylsilylimidazole+N-(Trimethylsilyl)acetamide→N,O-Bis(trimethylsilyl)acetamide
acetamide+N-trimethylsilylimidazole→N,O-Bis(trimethylsilyl)acetamide
acetamide+chlorotrimethylsilane→N,O-Bis(trimethylsilyl)acetamide

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	Polydimethyl siloxanes	-	1008.	custom temperature program

Precursor

N-SULFINYLACETAMIDE
acetamide
N-trimethylsilylimidazole
chlorotrimethylsilane

Downstream Product

N-[(4-methylphenyl)carbamothioyl]acetamide
N-methyl-1-phenyl-N-trimethylsilylmethanamine
5-fluoro-N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine
trimethyl(2-phenylpropan-2-yloxy)silane

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