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Mirtazapine

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Origin: China

Cas No: 85650-52-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 85650-52-8 Formula: C17H19N3 Molecular Weight: 265.35300

    Description

    An α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.

    Basic Info

    Chemical Name Mirtazapine
    Synonyms

    (14bR)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine;
    ORG-3770;
    1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2.1-A]PYRIDO[2.3-C][2]BENZAZEPINE;
    Mirtazapin;
    MIRTAZANINE;
    MIRTAZEPINE;
    1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE;
    REMERON;
    ZISPIN;
    MIRTAZAPINE ANHYDRUOS;

    CAS No. 85650-52-8
    Molecular Formula C17H19N3
    Molecular Weight 265.35300
    PSA 19.37000
    LogP 2.48180

    Properties

    Appearance & Physical State white solid
    Density 1.22g/cm3
    Boiling Point 432.4ºC at 760 mmHg
    Melting Point 114-116ºC
    Flash Point 215.3ºC
    Storage Condition Store at RT

    Safety Info

    Safety Statements S22-S24/25
    HS Code 2933990090
    WGK Germany 3
    Hazard Declaration H302; H336
    Symbol GHS07
    Caution Statement P301 + P312 + P330
    Signal Word Warning

    Synthesis Route

    2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol→Mirtazapine
    rac-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10-ol→Mirtazapine
    1-Oxo Mirtazapine (Mirtazapine Impurity C)→Mirtazapine

    Precursor

    2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol
    1-Oxo Mirtazapine (Mirtazapine Impurity C)
    rac-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10-ol
    1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine

    Downstream Product

    mirtazapinium hydrogenmaleate
    Mirtazapine Bromide
    8-Hydroxy Mirtazapine

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