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Mirtazapine

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Origin: China

Cas No: 85650-52-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 85650-52-8 Formula: C17H19N3 Molecular Weight: 265.35300

Description

An α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.

Basic Info

Chemical Name	Mirtazapine
Synonyms	(14bR)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; ORG-3770; 1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2.1-A]PYRIDO[2.3-C][2]BENZAZEPINE; Mirtazapin; MIRTAZANINE; MIRTAZEPINE; 1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE; REMERON; ZISPIN; MIRTAZAPINE ANHYDRUOS;
CAS No.	85650-52-8
Molecular Formula	C17H19N3
Molecular Weight	265.35300
PSA	19.37000
LogP	2.48180

Properties

Appearance & Physical State	white solid
Density	1.22g/cm3
Boiling Point	432.4ºC at 760 mmHg
Melting Point	114-116ºC
Flash Point	215.3ºC
Storage Condition	Store at RT

Safety Info

Safety Statements	S22-S24/25
HS Code	2933990090
WGK Germany	3
Hazard Declaration	H302; H336
Symbol	GHS07
Caution Statement	P301 + P312 + P330
Signal Word	Warning

Synthesis Route

2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol→Mirtazapine
rac-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10-ol→Mirtazapine
1-Oxo Mirtazapine (Mirtazapine Impurity C)→Mirtazapine

Precursor

2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol
1-Oxo Mirtazapine (Mirtazapine Impurity C)
rac-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10-ol
1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine

Downstream Product

mirtazapinium hydrogenmaleate
Mirtazapine Bromide
8-Hydroxy Mirtazapine

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