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(+)-Mirtazapine

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Origin: China

Cas No: 61337-87-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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CAS No.: 61337-87-9 Formula: C17H19N3 Molecular Weight: 265.35300

Description

Esmirtazapine (ORG-50,081) is a drug which was under development by Organon for the treatment of insomnia and vasomotor symptoms (e.g., hot flashes) associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology, including inverse agonist actions at H1 and 5-HT2 receptors and antagonist actions at α2-adrenergic receptors. As of March 2010, Merck terminated internal clinical development program for esmirtazapine, for hot flashes and insomnia, for strategic reasons.

Basic Info

Chemical Name	(+)-Mirtazapine
Synonyms	mirtazapine; (14b,S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (S)-mirtazepine; (S)-(+)-MIRTAZAPINE; (S)-1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; (S)-1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3c][2]benzazepine; (S)1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino-[2,1-a] pyrido [2,3-c] [2] benzazepin;
CAS No.	61337-87-9
Molecular Formula	C17H19N3
Molecular Weight	265.35300
PSA	19.37000
LogP	2.48180