Home > Carbonyl Compounds> methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate

methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate

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Origin: China

Cas No: 70667-26-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 70667-26-4 Formula: C23H38O6 Molecular Weight: 410.54400

Basic Info

Chemical Name	methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate
Synonyms	6-Oxo-17(S),20-dimethyl-PGE(1)-methylester; ornoprostil; Ornoprostilo; (17S)-17,20-dimethyl-6-oxo-PGE1 methyl ester; Ornoprostilum [Latin]; Ronoprost; Ornoprostilum; Ornoprostilo [Spanish];
CAS No.	70667-26-4
Molecular Formula	C23H38O6
Molecular Weight	410.54400
PSA	100.90000
LogP	3.37860

Properties

Density	1.112g/cm3
Boiling Point	549.8ºC at 760 mmHg
Flash Point	178.8ºC
Refractive Index	1.526

Synthesis Route

Ornoprostil bis-tert-butyldimethylsiloxy ether→methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate
6-trimethylsilylhex-5-ynoic acid→methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate
(3S,4R)-3-(Methoxymethyloxy)-2-methylidene-4-(tert-butyldimethylsiloxy)cyclopentanone→methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate

Precursor

(3S,4R)-3-(Methoxymethyloxy)-2-methylidene-4-(tert-butyldimethylsiloxy)cyclopentanone
6-trimethylsilylhex-5-ynoic acid methyl ester
6-trimethylsilylhex-5-ynoic acid
(R)-2-Bromomethyl-4-(tert-butyldimethylsiloxy)cyclopent-2-enone

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