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L-2-aminoadipic acid

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Origin: China

Cas No: 1118-90-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1118-90-7 Formula: C6H11NO4 Molecular Weight: 161.15600

Description

(2S)-2-Amino-hexanedioic Acid is used in the synthesis of orthogonally protected (2S)-2-Aminoadipic Acid. Also used in the synthesis of antitumoral PEG-gemcitabine prodrugs.

Basic Info

Chemical Name	L-2-aminoadipic acid
Synonyms	(2S)-2-aminohexanedioic acid; (S)-2-Aminohexanedioic Acid; L-a-Aminoadipic acid; (S)-2-Aminohexanedioic acid,L-Homoglutamic acid,Aad; L-2-AMinoadipic Acid;
CAS No.	1118-90-7
Molecular Formula	C6H11NO4
Molecular Weight	161.15600
PSA	100.62000
LogP	0.35350

Properties

Appearance & Physical State	white solid
Density	1.333 g/cm3
Boiling Point	364ºC at 760 mmHg
Melting Point	203-205ºC (dec.)
Flash Point	173.9ºC
Storage Condition	Store at RT.
Vapor Pressure	2.74E-06mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2922499990

Synthesis Route

δ-(L-α-aminoadipoyl)-L-serine-D-valine→D-valine+L-serine
(2RS)-α-Ethyl ω-methyl 2-(N-Acetylamino)adipate→D-2-aminoadipic acid+L-2-aminoadipic acid
(S)-2-(N-benzyl-N-benzyloxycarbonyl)aminoadipic acid→L-2-aminoadipic acid

Precursor

L-Homoglutamine
(2S)-2-(phenylmethoxycarbonylamino)hexanedioic acid
[(1S,2R)-2-(hydroxymethyl)cyclohexyl]methanol
(S)-2-(N-benzyl-N-benzyloxycarbonyl)aminoadipic acid

Downstream Product

glutaric acid
(2S)-2-(phenylmethoxycarbonylamino)hexanedioic acid
(2S)-6-oxopiperidine-2-carboxylic acid
2-oxoadipic acid

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