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Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)

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Origin: China

Cas No: 77307-50-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 77307-50-7 Formula: C25H24O12 Molecular Weight: 516.45100

Description

A potent and selective inhibitor of p90 Rsk, without inhibiting the function of upstream kinases such as MEK, Raf, or PKC.

Basic Info

Chemical Name	Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)
Synonyms	3',4'-Di-O-acetylafzelin;
CAS No.	77307-50-7
Molecular Formula	C25H24O12
Molecular Weight	516.45100
PSA	182.19000
LogP	1.92470

Properties

Density	1.572g/cm3
Boiling Point	753.017ºC at 760 mmHg
Melting Point	128-132ºC
Flash Point	255.567ºC
Refractive Index	1.666
Storage Condition	Store at -20ºC

Synthesis Route

5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)-3-[3,4-di-O-acetyl-2-O-benzyl-α-L-rhamnopyranosyloxy]-4H-chromen-4-one→Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)
(2S,3S,4S,5R,6S)-6-((5,7-bis(benzyloxy)-2-(4-(benzyloxy)phenyl)-4-oxo-4H-chromen-3-yl)oxy)-5-hydroxy-2-methyltetrahydro-2H-pyran-3,4-diyl diacetate→Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)
3-hydroxy-5,7-bis(phenylmethoxy)-2-(4-phenylmethoxyphenyl)chromen-4-one→Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside)

Precursor

(2S,3S,4S,5R,6S)-6-((5,7-bis(benzyloxy)-2-(4-(benzyloxy)phenyl)-4-oxo-4H-chromen-3-yl)oxy)-5-hydroxy-2-methyltetrahydro-2H-pyran-3,4-diyl diacetate
3-hydroxy-5,7-bis(phenylmethoxy)-2-(4-phenylmethoxyphenyl)chromen-4-one
5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)-3-[3,4-di-O-acetyl-2-O-benzyl-α-L-rhamnopyranosyloxy]-4H-chromen-4-one
5,7-bis(phenylmethoxy)-2-(4-phenylmethoxyphenyl)chromen-4-one

Downstream Product

afzelin

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