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Flavopiridol

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Origin: China

Cas No: 146426-40-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 146426-40-6 Formula: C21H20ClNO5 Molecular Weight: 401.84000

Description

Alvocidib (INN; also known as Flavopiridol or HMR-1275) is a flavonoid alkaloid CDK9 kinase inhibitor under clinical development for the treatment of acute myeloid leukemia, by Tolero Pharmaceuticals, Inc. It has been studied also for the treatment of arthritis and atherosclerotic plaque formation The target of Flavopiridol is the positive transcription elongation factor P-TEFb. Treatment of cells with Flavopiridol leads to inhibition of P-TEFb and the loss of mRNA production.

Basic Info

Chemical Name	Flavopiridol
Synonyms	Flavopirodol; Alvocidib,Free Base; Alvocidib;
CAS No.	146426-40-6
Molecular Formula	C21H20ClNO5
Molecular Weight	401.84000
PSA	94.14000
LogP	3.24250