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Evans blue

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Origin: China

Cas No: 314-13-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    314-13-6
    Other Names:
    Evans blue
    MF:
    C34H24N6Na4O14S4
    EINECS No.:
    206-242-5
    Place of Origin:
    Jiangsu, China
    Purity:
    /
    Classification:
    General Reagents
    Brand Name:
    NJDULY
    Model Number:
    SR0039
    Level:
    AR
    Content: dye content:
    ~ 80%
    Infrared spectrum identification:
    acceptable
    Loss on drying:
    ≤ 10.0%
    Property:
    Blue crystal
    Purpose:
    biochemical research
    Save:
    RT

    Packaging&Delivery

    Packaging Details
    Plastic bottle: 1g / bottle
    Need other packing, please contact customer service
    Port
    shanghai
    Lead Time:
    Quantity(Pieces)1 - 1>1
    Est. Time(days)7To be negotiated

  • Property

    CAS No.: 314-13-6 Formula: C34H24N6Na4O14S4 Molecular Weight: 960.80500

    Description

    T-1824 or Evans Blue, often incorrectly rendered as Evan's Blue, is an azo dye which has a very high affinity for serum albumin. Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma.
    Evans blue dye has been used as a viability assay on the basis of its penetration into non-viable cells, although the method is subject to error because it assumes that damaged or otherwise altered cells are not capable of repair and therefore are not viable.
    Evans blue is also used to assess the permeability of the blood–brain barrier to macromolecules. Because serum albumin cannot cross the barrier, and virtually all Evans Blue is bound to albumin, normally the neural tissue remains unstained. When the BBB has been compromised, albumin-bound Evans blue enters the CNS. It fluoresces with excitation peaks at 470 and 540nm and an emission peak at 680nm.
    Evans blue is pharmacologically active, acting as a negative allosteric modulator of the AMPA and kainate receptors and as an inhibitor of vesicular glutamate transporters. It also acts on P2 receptors.; It was named after Herbert McLean Evans, an American chemist.

    Basic Info

    Chemical Name Evans blue
    Synonyms

    evablin;
    GEIGY BLUE;
    t1824;
    evans blue tetrasodium salt;
    1,3-Naphthalenedisulfonic acid, 6,6‘-[(3,3‘-dimethyl[1,1‘-biphenyl]-4,4‘-diyl)bis(azo)]bis[4-amino-5-hydroxy-, tetrasodium salt;
    EVANS BLUE;
    diazobleu;
    blue Evan;
    Direct Blue 53;
    azovanblue;
    Evan's blue;
    DiazoBlue;

    CAS No. 314-13-6
    Molecular Formula C34H24N6Na4O14S4
    Molecular Weight 960.80500
    PSA 404.26000
    LogP 10.78520

    Properties

    Appearance & Physical State dark brown
    Stability Stable. Incompatible with strong reducing agents, strong oxidizing agents.
    Storage Condition Store at RT.

    Safety Info

    Safety Statements S16-S36/37-S45-S53
    WGK Germany 3
    Risk Statements R11; R45; R63
    Hazard Codes F

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