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ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate

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Origin: China

Cas No: 3543-73-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
3543-73-5
Other Names:
3543-73-5
MF:
C14H19N3O2
EINECS No.:
3543-73-5
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
≥99%
Brand Name:
Finerchem
Model Number:
3543-73-5
Application:
Bendamustine intermediate
Appearance:
White powder
Product name:
1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester
Molecular Weight:
261.32
Packaging&Delivery
Packaging Details
Aluminum foil bag for within 10kg
Fiber drum for 10kg and more
Port
SHANGHAI, BEIJING, QINGDAO, SHENZHEN
Lead Time:
Quantity(Kilograms) 1 - 10 >10
Est. Time(days) 2 To be negotiated

Property

CAS No.: 3543-73-5 Formula: C14H19N3O2 Molecular Weight: 261.32000

Description

Bendamustine intermediate.

Basic Info

Chemical Name	ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate
Synonyms	1H-benzimidazol-1-methyl-5-amino-2-butanoic acid ethyl ester; 5-amino-1-methyl-2-Benzimidazolebutyric acid ethyl ester; 4-(5-amino-1-methyl-1H-benzoimidazol-2-yl)-butyric acid ethyl ester; Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate; ethyl-4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl) butanoate; 5-Amino-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester; 1-Methyl-5-amino-1H-benzimidazole-2-butanoicacidethylester; ethyl 4-(5-amino-1-methyl-1H-benzimidazol-2-yl)butanoate;
CAS No.	3543-73-5
Molecular Formula	C14H19N3O2
Molecular Weight	261.32000
PSA	70.14000
LogP	2.62250

Properties

Appearance & Physical State	Brown solid
Density	1.21 g/cm3
Boiling Point	471.6ºC at 760 mmHg
Melting Point	130-135ºC
Flash Point	239ºC
Refractive Index	1.59

Safety Info

HS Code	2933990090

Synthesis Route

ethyl 4-(1-methyl-5-nitrobenzimidazol-2-yl)butanoate→ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate
2-Fluoro-5-nitroaniline→ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate
oxane-2,6-dione→ethyl 4-(5-amino-1-methylbenzimidazol-2-yl)butanoate

Precursor

ethyl 4-(1-methyl-5-nitrobenzimidazol-2-yl)butanoate
2-Fluoro-5-nitroaniline
4-(1-Methyl-5-nitro-1H-benzimidazol-2-yl)butanoic acid
oxane-2,6-dione

Downstream Product

4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
bendamustine HCL
[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic acid ethyl ester

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