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Ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate

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Origin: China

Cas No: 79199-62-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 79199-62-5 Formula: C9H17NO2 Molecular Weight: 171.23700

Description

Ethyl (2S,4R)-4-Methylpipecolate is an intermediate in the preparation of Argatroban.

Basic Info

Chemical Name	Ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate
Synonyms	ethyl 4-methyl-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid,4-Methyl-,ethyl ester; Ethyl-cis-4-methylpipecolat; ETHYL 4-METHYLNICOTINATE; 4-Methyl-nicotinsaeure-aethylester; 4-methylnicotinic acid ethyl ester; ethyl 4-methylpyridine-3-carboxylate;
CAS No.	79199-62-5
Molecular Formula	C9H17NO2
Molecular Weight	171.23700
PSA	38.33000
LogP	1.26640

Synthesis Route

ethyl cis-(2S,4R)-1-[(R)-1-phenylethyl]-4-methylpipecolate→Ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate
(6S)-1-[(R)-1-phenylethyl]-6-ethoxycarbonyl-4-methyl-3,4-didehydropiperidine→Ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate
isoprene→Ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate

Precursor

(6S)-1-[(R)-1-phenylethyl]-6-ethoxycarbonyl-4-methyl-3,4-didehydropiperidine
ethyl cis-(2S,4R)-1-[(R)-1-phenylethyl]-4-methylpipecolate
isoprene

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