Home > Carbonyl Compounds> Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride

Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride

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Origin: China

Cas No: 118111-54-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 118111-54-9 Formula: C22H29NO3 Molecular Weight: 355.47100

Description

Cyprodime is an opioid antagonist from the morphinan family of drugs.
Cyprodime is a selective opioid antagonist which blocks the μ-opioid receptor, but without affecting the δ-opioid or κ-opioid receptors. This makes it useful for scientific research as it allows the μ-opioid receptor to be selectively deactivated so that the actions of the δ and κ receptors can be studied separately, in contrast to better known opioid antagonists such as naloxone which block all three opioid receptor subtypes.

Basic Info

Chemical Name	Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride
Synonyms	Homoquinolinic acid; Cyprodime hydrochloride;
CAS No.	118111-54-9
Molecular Formula	C22H29NO3
Molecular Weight	355.47100
PSA	38.77000
LogP	3.04950

Properties

Density	1.21g/cm3
Boiling Point	504ºC at 760mmHg
Flash Point	258.6ºC
Refractive Index	1.598
Vapor Pressure	2.75E-10mmHg at 25°C

Synthesis Route

17-(cyclopropylmethyl)-4-hydroxy-14β-methoxymorphinan-6-one+Phenyltrimethylammonium Chloride→Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride
Naltrexone Hydrochloride→Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride
17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-6,14-dimethoxymorphinian→Cyprodime hydrochloride,17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride

Precursor

Naltrexone Hydrochloride
17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-6,14-dimethoxymorphinian
17-(cyclopropylmethyl)-4-hydroxy-14β-methoxymorphinan-6-one
Phenyltrimethylammonium Chloride

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