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Ceftiofur

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Origin: China

Cas No: 80370-57-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
80370-57-6
Other Names:
Ceftiofur
MF:
C19H17N5O7S3
EINECS No.:
80370-57-6
Place of Origin:
Shanghai, China
Type:
Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Blood System Agents, Cardiovascular Agents, Disinfectant and Preservatives, Electrolyte Balance and Dialysis Agents, Vitamins, Amino Acids and Coenzymes
Grade Standard:
Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade
Brand Name:
Terppon
Model Number:
822
Purity:
99%
Color:
white
Packaging&Delivery
Packaging Details
DRUMS
Port
Shanghai
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 20 To be negotiated

Property

CAS No.: 80370-57-6 Formula: C19H17N5O7S3 Molecular Weight: 523.56300

Description

Ceftiofur is an antibiotic of the cephalosporin type (third generation), licensed for use in veterinary medicine. It was first described in 1987. It is marketed by pharmaceutical company Zoetis as Excenel, Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.
It is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported.
The metabolite desfurolyceftiofur also has antibiotic activity. The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics).

Basic Info

Chemical Name	Ceftiofur
Synonyms	ceftiofur acid; EXCENEL; CEFTIFURHCL; CEFTIOFUR HCL; CeftiofurFreeAcid;
CAS No.	80370-57-6
Molecular Formula	C19H17N5O7S3
Molecular Weight	523.56300
PSA	256.26000
LogP	1.89100

Properties

Appearance & Physical State	White to off-white powder
Density	1.81 g/cm3
Refractive Index	1.819
Storage Condition	0-6ºC

Safety Info

HS Code	2941905700

Synthesis Route

cefotaxime+furan-2-carbothioic S-acid→Ceftiofur
furan-2-carbothioic S-acid+cefotaxime sodium→Ceftiofur
4-chloro-2-methoxyimino-3-oxobutanoic acid+trimethylsilyl (6R,7R)-7-amino-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate→Ceftiofur

Precursor

cefotaxime
trimethylsilyl (6R,7R)-7-amino-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
furan-2-carbothioic S-acid
4-chloro-2-methoxyimino-3-oxobutanoic acid

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